A study headed by researchers at the Centre for Genomic Regulation (CRG) in Barcelona has provided for the first time evidence that a single drug, already licensed for medical use, can stabilize ...
The HGBA N370S/Gba−/− mouse carries a mutated human N370S HGBA transgene on a mouse Gba1 null (Gba−/−) background (Sanders et al., 2013). The mating scheme to achieve this genetic combination is to ...
(Left) Correction of pathogenic Csf1r mutation by Mr BMT effectively rescues pathological changes in the brain, motor impairment and cognitive decline in ALSP mice. (Right) tBMT-mediated microglia ...
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